Layanan journal yang disediakan oleh Perpustakaan Universitas Gunadarma
| Judul Artikel | : | Celiac Disease at Several Hospitals in Jakarta, Indonesia |
|---|---|---|
| Judul Terbitan | : | Acta Medica Indonesiana: The Indonesian Journal of Internal Medicine |
| ISSN | : | 01259326 |
| Bahasa | : | IND |
| Tempat Terbit | : | jakarta |
| Tahun | : | 0000 |
| Volume | : | Vol. 42 Issue 4 0000 |
| Penerbit | : | Interna Publishing |
| Frekuensi Penerbitan | : | |
| Penulis | : | Marcellus Simadibrata |
| Abstraksi | : | 1n Indonesia, no study has reported celiac disease. The present study is conducted to obtain characteristics, clinical data, endoscopic and histopathological features of patients with celiac disease. The study was conducted in patients with chronic diarrhea at several hospitals in Jakarta between 1995 and 2009. Patients were considered as having positive celiac disease and were included in the study if they had complaint of chronic diarrhea, villous atrophy at descend- ing duodenum/jejunum as categorized in Marsh criteria and positive serology on serum anti-gliadin antibody. As the histopathological control, there were 37 normal mucosa biopsies of duodenum and jejunum in patients with dyspepsia who had normal endoscopic appearance. Of 819 chronic diarrhea cases, there were 5 (0.61 %) cases of celiac disease with subject characteristics as follows: men (3pts), age 50-59 years (3p ts) , Chinese (3p ts) , well- financial status (5pts), good hygiene and sanitation (5pts), /oose-, non-steatorea and unbleeding stools (5pts) and 6 months diarrhea duration (3pts). Celiac disease was found more frequently in subjects with malnutrition (3pts), anemia (3pts) and hypoalbuminemia (3pts). Most of histo- pathological examination demonstrated total villous atrophy of the small intestines (3pts). Measurement of small intestinal villous mucosa revealing the mean value of vil- lous mucosa in patients with celiac disease was 40 ± 14.14 /1; while in normallcontrol subjects, the mean value was 341.76 ± 76.06 JL The height of crypt, villi width and inter- villous space were different from control. Lymphocytes in the mucosa and intraepithelium were higher than control. Celiac disease is found in 0.61% cases of chronic diarrhea. The characteristics of subjects mostly include men, Chinese ethnicity, age 50-59 years, good-financial status, good hygiene and sanitation, 6-month diarrhea, malnutrition, anemia and hypoalbuminemia. In celiac disease, mucosa villous atrophy and other changes of intestinal mucosa can be found. |
| Kata Kunci | : | celiac disease; villous atrophy; characteristics; physical examination; histopathology. |
| Lokasi | : | P231 |
| Terakreditasi | : | sudah |