Layanan journal yang disediakan oleh Perpustakaan Universitas Gunadarma
| Judul Artikel | : | Central nervous system lymphoma: a description and analysis of patients clinical and radiological features |
|---|---|---|
| Judul Terbitan | : | Medical Journal of Indonesia |
| ISSN | : | 08531773 |
| Bahasa | : | ENG |
| Tempat Terbit | : | Jakarta |
| Tahun | : | 0000 |
| Volume | : | Vol. 23 Issue 3 0000 |
| Penerbit | : | Faculty of Medicine Universitas Indonesia |
| Frekuensi Penerbitan | : | - |
| Penulis | : | Julius July, Andy Wijaya,Priscilla Muliantara,Mira Yuniarti |
| Abstraksi | : | Background: Central nervous system (CNS) lymphoma is a rare brain neoplasm. Its incidence has increased these years, so it should be considered in the differential diagnosis for mass lesions in the CNS. The aim of the study was to describe the radiological and clinical features of patients with CNS lymphoma. Methods: The study was a retrospective study. All patients histopathologically confirmed to have CNS lymphoma from November 2008 to December 2013 in Siloam Hospital Lippo Village were included in the study. Medical records and patients MRl results were retrieved to be analyzed. Results: 32 patients were histopathologically diagnosed to have CNS lymphoma. The patients, mean age was 54 ± 15.01 years with slight male predominance. No patient was immuno compromised (CD4 > 500 cells/ul, and leukocyte 5,000-11,000 cells/ul.). The median interval between the onset of the initial symptoms and diagnosis is 7 weeks. The most common presenting symptoms were headache, mental changes, and neurological deficits related to the location oflesion. MR images show that most lesions were enhanced with contrast, iso-hypointense in TI weighted imaging (T 1 Wl), iso- to hypointense with perifocal edema in T2 weighted imaging (T2WI), hyperintense in diffusion weighted imaging (OWl), with the most common location was white matter of cerebral hemisphere on one or more lobes and periventricular area, and the tumor could be single or multiple (24%) without clear edges. Conclusion: Short course of neurological worsening (within weeks) should lead a suspicion toward lymphoma. The characteristics of MR images are markedly enhanced by contrast, iso- to hypointense on Tl WI and T2WI, and hyperintense in OWl, involving white matter of cerebral hemisphere and peri ventricular area. |
| Kata Kunci | : | central nervous system lymphoma; magnetic resonance imaging |
| Lokasi | : | P154 |
| Terakreditasi | : | belum |