JOURNAL

Layanan journal yang disediakan oleh Perpustakaan Universitas Gunadarma

Diagnostic Value of Quantitative Rapid Test Cardiac Troponin I In Acute Myocardial Infarction Patients

Judul Artikel:Diagnostic Value of Quantitative Rapid Test Cardiac Troponin I In Acute Myocardial Infarction Patients
Judul Terbitan:Medika (Jurnal Kedokteran Indonesia) Tahun 2011
ISSN:0216-0910
Bahasa:IND
Tempat Terbit:Jakarta
Tahun:0000
Volume:Vol. 37 Issue 04 0000
Penerbit:PT. Grafiti Medika Pers
Frekuensi Penerbitan:12 x 1 tahun
Penulis:ANIK WIDIJANTI, SITI FATONAH, TINNY ENDANG HERNOWATI
Abstraksi:Cardiac Troponin I (cTnI) is the most sensitive and specific biochemical markers for myocardial damag­e but its diagnostic value has a high variability. It is necessary to determine diagnostic value for a new kit of cTnI. The aim of our study is to evaluate the diagnostic value of quantitative rapid test cardia­c troponin I (cTnI) as a marker of myocardial infarction. A cross sectional study in AMI (Acute Myocardial infarction) patients compared with NON AMI patients as control. The level of cTnI was measure­d by Quantitative Rapid Test Troponin I and continued with determining the diagnostic value of cTnI at various cut off. From February – December 2007 we obeserve 67 patients AMI and 56 patient NON AMI. The diagnostic value [sensitivity, specificity, positive predictive value (PPV) and negative pre­dicti­ve value (NPV)] of Quantitative Rapid Test Troponin I with cut off value 1.0 ng/ml (recommended in the manufacturer’s package), is respectively 91.0%, 91.1%, 92.4%, and 89.5%, with area under curve 0.911. The diagnostic value of Quantitative Rapid Test cTnI then determined in various cut off value (0.8, 1.0, 1.2, 1.5, and 2.0 ng/ml). We find that the area under curve of Quantitative Rapid Test cTnI in these various cut off value respectively 0.926, 0.911, 0.915, 0.902, and 0.849. The sensitivity respectively 94.0%, 91.0%, 86.6%, 82.1% and 71.6% and the specificity 91.1%, 91.1%, 96.4%, 98.2% and 98.2%. The Troponin I Quantitative rapid test was sensitive and specific to diagnose acute myocardial infarction, with the best area under curve 0.926 in cut off value cTnI 0.8 ng/ml.
Kata Kunci:cTnI; AMI; diagnostic value ( sensitivity and specificity).
Lokasi:P236
Terakreditasi:sudah