JOURNAL

Layanan journal yang disediakan oleh Perpustakaan Universitas Gunadarma

REACTIONS OF CISPLATIN HYDROLYTES WITH THIOLS. 3: REACTIONS OF cis-[PtC5NH3)2(H20)2]2+WITH GLUTATHIONE

Judul Artikel:REACTIONS OF CISPLATIN HYDROLYTES WITH THIOLS. 3: REACTIONS OF cis-[PtC5NH3)2(H20)2]2+WITH GLUTATHIONE
Judul Terbitan:Makara Seri Sains
ISSN:1693-6671
Bahasa:IND
Tempat Terbit:Depok
Tahun:0000
Volume:Vol. 10 Issue 1 0000
Penerbit:Gedung DRPM-UI, Kampus Universitas Indonesia
Frekuensi Penerbitan:2x setahun
Penulis:Sutopo Hadi
Abstraksi:The reaction of ciS-[pt('5NH3h(H20)z]2+ (3) with glutathione (GSH) was investigated in aqueous solution. In this reaction, the ammine in the platinum complex formed was liberated. Surprisingly two chelate rings were observed, six¬membered-S,D-chelate ring complex ciS-[pt(15NH3h(SG-S,D) (7) and five-membered-S,N-chelate ring complex cis¬[PtC5NH3h(SG-S,N)] (8). The bis (thiolate) platinum(II) complex, ciS-[pt('5NH3h(SG)z] (9) was always r.resent in this reaction in any mole ratio used. The dinuclear sulphur-bridged complex (10), giving a broad peak in 1 N NMR, was only present in very tiny amounts.
Kata Kunci:N NMR; Glutahione
Lokasi:P19
Terakreditasi:belum